真菌医学研究センター

研究キーワード

気管支鏡 ,COPD ,肺癌 ,気管支喘息 ,間質性肺疾患 ,肺循環障害 ,睡眠呼吸障害 ,呼吸不全 ,呼吸調節 ,Lung Cancer ,Asthma Bronchiale ,Interstitial pulmonary disease ,Pulmonary vascular remodeling ,Pulmonary hypertension ,Sleep Oxygen desaturation ,Sleep apnea ,Respiratory Failure ,Control of Breathing

研究分野

ライフサイエンス / 呼吸器内科学 /

経歴

12 3 >

1986年4月

-医員（小田原市立病院）

1986年4月

-Doctor (Odawara City Hospital)

1983年4月

-医師（千葉大学医学部呼吸器内科）

1983年4月

-Doctor (Chiba University School of Medicine)

1981年4月

-医師（都立府中病院）

学歴

千葉大学医学部

Chiba University School of Medicine

受賞

基礎的、臨床的研究）

1994 胸部疾患学会奨励賞（女性ホルモンの呼吸調節におよぼす

respiratory control)

clinical study in effects of female hormones on

1994 Award in Japanese Respiratory Society (Basic and

論文

12 3 4 5 >

Effects of Anti-Fibrotic Drugs on Transcriptome of Peripheral Blood Mononuclear Cells in Idiopathic Pulmonary Fibrosis

Daisuke Ishii Takeshi Kawasaki Hironori Sato Koichiro Tatsumi Takuro Imamoto Keiichiro Yoshioka Mitsuhiro Abe Yoshinori Hasegawa Osamu Ohara Takuji Suzuki

International Journal of Molecular Sciences 25(7) 3750-3750 2024年3月

Two anti-fibrotic drugs, pirfenidone (PFD) and nintedanib (NTD), are currently used to treat idiopathic pulmonary fibrosis (IPF). Peripheral blood mononuclear cells (PBMCs) are immunocompetent cells that could orchestrate cell–cell interactions as...

Functional roles of CD26/DPP4 in lipopolysaccharide-induced lung injury.

Shun Sato Takeshi Kawasaki Ryo Hatano Yu Koyanagi Yukiko Takahashi Kei Ohnuma Chikao Morimoto Steven M Dudek Koichiro Tatsumi Takuji Suzuki

American journal of physiology. Lung cellular and molecular physiology 2024年3月

Acute respiratory distress syndrome (ARDS) is characterized by dysregulated inflammation and increased permeability of lung microvascular cells. CD26/Dipeptidyl peptidase-4 (DPP4) is a type II membrane protein that is expressed in several cell typ...

Identification of kynurenine and quinolinic acid as promising serum biomarkers for drug-induced interstitial lung diseases.

Yuchen Sun Kosuke Saito Atsuhito Ushiki Mitsuhiro Abe Yoshinobu Saito Takeru Kashiwada Yasushi Horimasu Akihiko Gemma Koichiro Tatsumi Noboru Hattori Kenji Tsushima Kazuhisa Takemoto Rika Ishikawa Toshiko Momiyama Shin-Ichiro Matsuyama Noriaki Arakawa Hirotoshi Akane Takeshi Toyoda Kumiko Ogawa Motonobu Sato Kazuhiko Takamatsu Kazuhiko Mori Takayoshi Nishiya Takashi Izumi Yasuo Ohno Yoshiro Saito Masayuki Hanaoka

Respiratory research 25(1) 31-31 2024年1月

BACKGROUND: Drug-induced interstitial lung disease (DILD) is a lung injury caused by various types of drugs and is a serious problem in both clinical practice and drug development. Clinical management of the condition would be improved if there we...

Functional Roles of CD26/DPP4 in Bleomycin-Induced Pulmonary Hypertension Associated with Interstitial Lung Disease

2024年1月 [査読有り]

Different Transcriptome Features of Peripheral Blood Mononuclear Cells in Non-Emphysematous Chronic Obstructive Pulmonary Disease

Takuro Imamoto Takeshi Kawasaki Hironori Sato Koichiro Tatsumi Daisuke Ishii Keiichiro Yoshioka Yoshinori Hasegawa Osamu Ohara Takuji Suzuki

International Journal of Molecular Sciences 2023年12月 [査読有り]