The search for human cancer viruses triggered by the discovery of animal tumor viruses in the early twentieth century was unsuccessful until the end of the 1970s, although the concept of oncogenes and tumor-suppressor genes developed by the resear...
International journal of pharmaceutics 496(2) 401-6 2015年12月 [査読有り]
Some tumor-specific near-infrared (NIR) fluorescent dyes such as indocyanine green (ICG), IDRye800CW, and 5-aminolevulinic acid have been used clinically for detecting tumor margins or micro-cancer lesions. In this study, we evaluated the physicoc...
PEDIATRIC SURGERY INTERNATIONAL 31(12) 1151-1159 2015年12月 [査読有り]
With current treatment regimens, high-risk neuroblastoma (NB) remains largely incurable. Oncolytic viral therapy uses replication-competent viruses, like Sindbis virus (SINV), to kill cancers. The SINV AR339 strain is blood borne and relatively no...
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 466(3) 567-571 2015年10月 [査読有り]
Epigenetics plays a role in the regulation of gene expression. Epigenetic changes control gene expression at the transcriptional level. Our previous study suggested that the La protein, which is mainly localized in the nucleus, was associated with...
大学院国際学術研究院