Yasushi Yoshida   Tatsuya Ao   Takashi Mino   Masami Sakamoto   
MOLECULES 28(1) 2023年1月
There has been a great focus on halogen-bonding as a unique interaction between electron-deficient halogen atoms with Lewis basic moieties. Although the application of halogen-bonded atoms in organic chemistry has been eagerly researched in these ...
European Journal of Organic Chemistry 2022(30) 2022年8月
Acetyl-substituted 7,12-dihydrobenzo[de]indolo[3,2-b]quinoline was developed as a N-substituted polycyclic heteroaromatic molecule via Pd-catalyzed cyclo-isomerization of an alkyne precursor, followed by intramolecular Goldberg amination. This com...
Norika Miyazaki   Kazutaka Sanada   Takumi Nakamura   Aoi Washio   Yasushi Yoshida   Takashi Mino   Yoshio Kasashima   Masami Sakamoto   
Crystal Growth and Design 22(8) 4673-4679 2022年8月
The asymmetric amplification of p-anisoin was studied by attrition-enhanced deracemization in the presence of chiral standard amino acids. In this reaction, p-anisoin crystallized as a conglomerate, and deracemization under basic conditions was ef...
Kazutaka Sanada   Aoi Washio   Hiroki Ishikawa   Yasushi Yoshida   Takashi Mino   Masami Sakamoto   
Angewandte Chemie - International Edition 61(19) 2022年5月
We developed a chiral symmetry breaking method for monoacylated meso diols. The X-ray crystal structure analysis of monoacylated 1,4-anhydroerythritols, meso cyclic diols with a cis configuration, revealed that the O-(p-anisoyl) derivative crystal...