Angewandte Chemie International Edition 60(23) 12819-12823 2021年6月
The study of chirogenesis of organic molecules is important to elucidate the origin of the homochirality of biomolecules on Earth. Here, we have accomplished chiral symmetry breaking from a racemate using optical vortices with orbital angular mome...
The highly enantioselective synthesis of p-anisoin was achieved via the benzoin condensation of a prochiral p-anisaldehyde using achiral NHC catalysts such as vitamin B1. In this reaction, p-anisoin crystallized as a conglomerate, and the deracemi...
<p>α-Tetrasubstituted-α-amino thioesters were synthesised through chiral phase-transfer catalysed Michael reaction of imino thioesters in up to 97% yield with up to 81% ee.</p>