Hiroshi Yuita   Isaac F López-Moyado   Hyeongmin Jeong   Arthur Xiuyuan Cheng   James Scott-Browne   Jungeun An   Toshinori Nakayama   Atsushi Onodera   Myunggon Ko   Anjana Rao   
Proceedings of the National Academy of Sciences of the United States of America 120(6) e2214824120 2023年2月
The three mammalian TET dioxygenases oxidize the methyl group of 5-methylcytosine in DNA, and the oxidized methylcytosines are essential intermediates in all known pathways of DNA demethylation. To define the in vivo consequences of complete TET d...
Proceedings of the National Academy of Sciences of the United States of America 120(2) e2218345120 2023年1月 [査読有り]
CD4+ memory T cells are central to long-lasting protective immunity and are involved in shaping the pathophysiology of chronic inflammation. While metabolic reprogramming is critical for the generation of memory T cells, the mechanisms controlling...
Frontiers in Immunology 13 1036672-1036672 2023年1月 [査読有り]
Introduction
Kawasaki disease (KD) is an acute systemic vasculitis that predominantly afflicts children. KD development is known to be associated with an aberrant immune response and abnormal platelet activation, however its etiology is still lar...
Okano, M   Hirahara, K   Kiuchi, M   Onoue, M   Iwamura, C   Kokubo, K   Hishiya, T   Morimoto, Y   Ikehara, Y   Murakami, A   Ebihara, N   Nakayama, T