Atsushi Onodera   Edahí González-Avalos   Chan-Wang Jerry Lio   Romain O. Georges   Alfonso Bellacosa   Toshinori Nakayama   Anjana Rao   
Genome Biology 22(1) 186-186 2021年12月 [査読有り]
<title>Abstract</title><sec>
<title>Background</title>
TET enzymes mediate DNA demethylation by oxidizing 5-methylcytosine (5mC) in DNA to 5-hydroxymethylcytosine (5hmC), 5-formylcytosine (5fC), and 5-carboxylcytosine (5caC). Since these oxidize...
Murshed H. Sarkar   Ryoji Yagi   Yukihiro Endo   Ryo Koyama-Nasu   Yangsong Wang   Ichita Hasegawa   Toshihiro Ito   Ilkka S. Junttila   Jinfang Zhu   Motoko Y. Kimura   Toshinori Nakayama   
PLOS ONE 16(11) e0260204-e0260204 2021年11月 [査読有り]
While IFNγ is a well-known cytokine that actively promotes the type I immune response, it is also known to suppress the type II response by inhibiting the differentiation and proliferation of Th2 cells. However, the mechanism by which IFNγ suppres...