Pharmacology, biochemistry, and behavior 211 173288-173288 2021年12月
BACKGROUND: The excessive blockade of dopamine D2 receptors (DRD2s) with long-term antipsychotic treatment is known to induce a dopamine supersensitivity state (DSS). The mechanism of DSS is speculated to be a compensatory up-regulation of DRD2s, ...
Annals of General Psychiatry 20(1) 2021年12月 [査読有り]
<title>Abstract</title><sec>
<title>Background</title>
To control the spread of the new SARS-CoV-2 infection's disease (COVID-19), appropriate precautionary behaviors by the public should be promoted. There are international differences in publi...
Tamaki Ishima Sebastian Illes Yoshimi Iwayama Brian Dean Takeo Yoshikawa Hans Ågren Keiko Funa Kenji Hashimoto
Journal of Affective Disorders 290 61-64 2021年7月 [査読有り]
Background: Brain-derived neurotrophic factor (BDNF) antisense RNA (BDNF-AS) was identified as naturally conserved non-coding antisense RNA that suppresses the transcription of BDNF. Methods: We measured the expression of BDNF mRNA and BDNF-AS mRN...
Yaoyu Pu Jun Yang Lijia Chang Youge Qu Siming Wang Kai Zhang Zhongwei Xiong Jiancheng Zhang Yunfei Tan Xingming Wang Yuko Fujita Tamaki Ishima Debin Wan Sung Hee Hwang Bruce D. Hammock Kenji Hashimoto
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 118(5) 2021年2月
Ketamine: From Abused Drug to Rapid-Acting Antidepressant 1-189 2020年1月
This book presents the latest data from basic research and clinical trials supporting the effectiveness of ketamine as a treatment for depression, bipolar disorder, and suicidal behavior, setting these positive findings within the context of the s...
大学院国際学術研究院