BACKGROUND: Brain-derived neurotrophic factor (BDNF) antisense RNA (BDNF-AS) was identified as naturally conserved non-coding antisense RNA that suppresses the transcription of BDNF. METHODS: We measured the expression of BDNF mRNA and BDNF-AS mRN...
Youge Qu   Jiajing Shan   Siming Wang   Lijia Chang   Yaoyu Pu   Xingming Wang   Yunfei Tan   Masayuki Yamamoto   Kenji Hashimoto   
European archives of psychiatry and clinical neuroscience 271(3) 439-446 2021年4月
The transcription nuclear factor-erythroid factor 2-related factor 2 (Nrf2) plays a key role in inflammation that is involved in depression. We previously reported that Nrf2 knock-out (KO) mice exhibit depression-like phenotypes through systemic i...
Yaoyu Pu   Jun Yang   Lijia Chang   Youge Qu   Siming Wang   Kai Zhang   Zhongwei Xiong   Jiancheng Zhang   Yunfei Tan   Xingming Wang   Yuko Fujita   Tamaki Ishima   Debin Wan   Sung Hee Hwang   Bruce D. Hammock   Kenji Hashimoto   
Proceedings of the National Academy of Sciences of the United States of America 118(5) 2021年2月
The authors note that the author name Debin Wang should instead appear as Debin Wan. The corrected author line appears below. The online version has been corrected.
Tomihisa Niitsu   Yasunori Oda   Keita Idemoto   Kiyomitsu Ota   Jing Liu   Tsuyoshi Sasaki   Michiko Nakazato   Kenji Hashimoto   Masaomi Iyo   
Psychiatry research 296 113674-113674 2021年2月
Glial cell line-derived neurotrophic factor (GDNF) may play an important role in attention. We investigated the association between serum GDNF levels and clinical status in unmedicated adults with attention deficit/hyperactivity disorder (ADHD) (n...
Yaoyu Pu   Jun Yang   Lijia Chang   Youge Qu   Siming Wang   Kai Zhang   Zhongwei Xiong   Jiancheng Zhang   Yunfei Tan   Xingming Wang   Yuko Fujita   Tamaki Ishima   Debin Wan   Sung Hee Hwang   Bruce D. Hammock   Kenji Hashimoto   
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 118(5) 2021年2月
Kenji Hashimoto   Soichiro Ide   Kazutaka Ikeda   
Ketamine: From Abused Drug to Rapid-Acting Antidepressant 1-189 2020年1月
This book presents the latest data from basic research and clinical trials supporting the effectiveness of ketamine as a treatment for depression, bipolar disorder, and suicidal behavior, setting these positive findings within the context of the s...