Pediatric surgery international 39(1) 23-23 2022年11月
PURPOSE: Although the impairment of regulatory T-cells (Tregs) has been shown in the liver or portal area of biliary atresia (BA) the frequency and function of circulating Tregs in BA patients is poorly understood. We aimed to investigate the freq...
Eizo Watanabe Toshinobu Akamatsu Masaaki Ohmori Mayu Kato Noriko Takeuchi Naruhiko Ishiwada Rintaro Nishimura Haruka Hishiki Lisa Fujimura Chizuru Ito Masahiko Hatano
Cytokine 149 155723-155723 2022年1月
PURPOSE: The anticoagulant agent recombinant thrombomodulin (rTM) activates protein C to prevent excessive coagulation and also possibly regulates hyper-inflammation via neutralization of high-mobility-group B1 (HMG-B1). The glycocalyx layer in en...
The Kif26a protein-coding gene has been identified as a negative regulator of the GDNF-Ret signaling pathway in enteric neurons. The aim of this study was to investigate the influence of genetic background on the phenotype of Kif26a-deficient (KO,...
International journal of oncology 43(6) 1855-63 2013年12月
Our recent studies of microRNA (miRNA) expression signatures indicated that microRNA-29a (miR-29a) was significantly downregulated in several types of human cancers, suggesting that miR-29a may be a putative tumor-suppressive miRNA in human cancer...
Doxorubicin is one of the most effective drugs available for cancer chemotherapy. However, the clinical use of doxorubicin has been greatly limited because of severe side effects on cardiomyocytes. Since Nd1-L, a novel actin-binding protein, is ex...
We have identified the murine Clast1/LR8 gene by subtraction of cDNA derived from CD40 ligand-activated and naive B cells. The Clast1 gene is ubiquitously expressed in various organs of adult mice. However, its physiological function was largely u...
A Inoue MM Kang L Fujimura Y Takamori K Sasagawa H Itoh T Tokuhisa M Hatano
DNA AND CELL BIOLOGY 24(1) 30-34 2005年1月
The murine Nd1 gene encodes two forms of protein, Nd1-L and Nd1-S, both of which share the BTB/POZ domain, but Nd1-S lacks the kelch repeats. Although Nd1-L ubiquitously expresses, localizes in the cytoplasm and functions as a stabilizer of actin ...
大学院国際学術研究院