The role of immune checkpoint inhibitors in metastatic lung cancer has been established in recent years and the pretherapeutic profiles of the tumor microenvironment in responders have been increasingly reported. The role of salvage surgery and th...
Cancer immunology, immunotherapy : CII 68(12) 1935-1947 2019年12月 [査読有り]
BACKGROUND: Due to the strong tumoricidal activities of activated natural killer T (NKT) cells, invariant NKT cell-based immunotherapy has shown promising clinical efficacy. However, suppressive factors, such as regulatory T cells (Tregs), may be ...
Dendritic cells (DC) play a key role in the initiation of both antitumor immunity and immunological tolerance. It has been demonstrated that exposure to soluble factors produced by tumor cells modulates DC functions and induces tolerogenic DC diff...
Tanaka K   Kanesaka Y   Takami M   Suzuki A   Hosokawa H   Onodera A   Kamata T   Nagato K   Nakayama T   Yoshino I   Motohashi S   
Biochemical and biophysical research communications 506(1) 27-32 2018年11月 [査読有り]
Hara, A   Nasu, R   Takami, M   Hirono, S   Matsutani, T   Nakayama, T   Iwadate, Y   Motohashi, S   
Hara, A   Nasu, R   Takami, M   Hirono, S   Matsutani, T   Nakayama, T   Iwadate, Y   Motohashi, S   
Aoki, T   Takami, M   Takatani, T   Motoyoshi, K   Ishii, A   Hara, A   Hino, M   Shimojo, N   Motohashi, S   
Yoshizawa, H   Harada, K   Ishii, A   Mise, N   Hishiki, T   Saito, K   Nakata, M   Komatsu, S   Nakayama, T   Yoshida, H   Takami,M   Motohashi, S