学術研究・イノベーション推進機構
研究者氏名 西田 篤司
ニシダ アツシ URL 所属 千葉大学 部署 学術研究・イノベーション推進機構 職名 特任教授 学位 薬学博士(北海道大学) J-Global ID 200901074908564750
研究キーワード
有機合成化学
,synthetic organic chemistry
受賞
2020年3月
日本薬学会, 薬学会賞,新規反応開発を基盤とする多環性天然物合成
2004年3月
日本薬学会, 学術振興賞,新規骨格構築法の開発と天然物合成への応用
論文
Shigeru Arai   Koki Matsumoto   Atsushi Nishida   
Tetrahedron 75(9) 1145-1148 2019年3月 [査読有り]
© 2018 Regio- and stereoselective sulfonylation of allenes under Cu catalysis is described. Allenyl sp carbons exclusively react with TsCN to give the corresponding alkenyl sulfones. The reaction is initiated by addition of tosyl radical to form b...
Roxana Filip   Tyler A. Shaw   Atsushi Nishida   John Paul Pezacki   
MedChemComm 10(6) 985-990 2019年 [査読有り]
© 2019 The Royal Society of Chemistry. Fungi, including mushrooms and mycelia, are a rich source for natural products with medicinal properties. In some cases, they can lead to opportunistic infections in humans and other mammals. In 1994, the fir...
Hiroto Hori   Shigeru Arai   Atsushi Nishida   
Organic and Biomolecular Chemistry 17(19) 4783-4788 2019年 [査読有り]
© 2019 The Royal Society of Chemistry. An efficient synthesis of carbo-and heterocycles using CC, CO and CN bonds under cobalt catalysis is described. The substituents on olefins are key for controlling the regio-and chemoselectivity in the initia...
Yabin Wang   Junya Kasahara   Kazuyuki Yamagata   Hiroyuki Nakamura   Toshihiko Murayama   Noriyuki Suzuki   Atsushi Nishida   
Bioorganic and Medicinal Chemistry Letters 28(19) 3222-3226 2018年10月 [査読有り]
© 2018 Elsevier Ltd A new ceramide analog, 1, containing two fluorescent dyes, NBD in the N-acyl part and KFL5 in the alkyl part, was synthesized. The fluorescence from both NBD and KFL5 was detected in living cells in a time-dependent manner. A m...
Takuya Takeda   Shinji Harada   Akito Okabe   Atsushi Nishida   
Journal of Organic Chemistry 83(19) 11541-11551 2018年10月 [査読有り]
© 2018 American Chemical Society. A new approach for the synthesis of highly functionalized tetrahydrocyclohepta[b]indoles through [5 + 2] cycloaddition was developed. Two carbon-carbon bonds were formed by the simple addition of an indium catalys...
MISC
Shigeru Arai   Yuka Amako   Hiroto Hori   Atsushi Nishida   
Yuki Gosei Kagaku Kyokaishi/Journal of Synthetic Organic Chemistry 77(4) 341-350 2019年 [査読有り]
© 2019 Society of Synthetic Organic Chemistry. All rights reserved. Since a cyano group can be transformed to carboxylic acids, amino- and hydroxymethyl groups as well as aldehydes, its installation, particularly catalytic protocol, has been one o...
Shigeru Arai   Masaya Nakajima   Atsushi Nishida   
Yuki Gosei Kagaku Kyokaishi/Journal of Synthetic Organic Chemistry 76(7) 668-677 2018年 [査読有り]
© 2018 Society of Synthetic Organic Chemistry. Lundurines A-D were isolated in 1995 from the Malayan plant Kopsia tenuis, which has been used in folk medicine and is a rich source of biologically active alkaloids. Their intriguing hexacyclic frame...
Shigeru Arai   Masaya Nakajima   Atsushi Nishida   
Alkaloids: Chemistry and Biology 78 167-204 2017年 [査読有り]
© 2017 Elsevier Inc. This review focuses on the total synthesis of lundurines A–C. Their main structural feature is a unique cyclopropa[b]indole core that has been found only in these alkaloids. In addition to this characteristic structure, the bi...
Minoru Isobe   Atsushi Nishida   Yeun-Mun Choo   Noorsaadah Abd. Rahman   Poonsakdi Ploypradith   Somsak Ruchirawat   Guo-Qiang Lin   Ang Li   Zhu-Jun Yao   Biing-Jiun Uang   Chun-Chen Liao   Pauline Chiu   Byeong Moon Kim   Teck Peng Loh   
Chemistry - An Asian Journal 10(4) 790-804 2015年 [査読有り]
Yuki Gosei Kagaku Kyokaishi/Journal of Synthetic Organic Chemistry 73(3) 254-265 2015年
We have established aromatic enamide-ene metathesis to give highly substituted indole derivatives. This is a new method for the preparation of chiral 2-trans-cyclopropyl indoles, which successfully led to our H 4 antagonist candidates. Based on th...