Yu Takahashi   Shintaro Sato   Yosuke Kurashima   Chen-Yi Lai   Makoto Otsu   Mikio Hayashi   Takayuki Yamaguchi   Hiroshi Kiyono   
EBioMedicine 23 34-45 2017年9月 [査読有り]
Visceral fat accumulation as observed in Crohn's disease and obesity is linked to chronic gut inflammation, suggesting that accumulation of gut adipocytes can trigger local inflammatory signaling. However, direct interactions between intestinal ep...
Joo S.   Fukuyama Y.   Park EJ.   Yuki Y.   Kurashima Y.   Ouchida R.   Ziegler SF.   Kiyono H.   
Mucosal Immunology 10(4) 901-911 2017年7月 [査読有り]
Thymic stromal lymphopoietin (TSLP) is an interleukin-7 (IL-7)-like cytokine involved in T helper 2 type immune responses. The primary target of TSLP is myeloid dendritic cells (DCs), however, little is known about the mechanism by which TSLP elic...
Mast cells are important for eradication of intestinal nematodes; however, their precise mechanisms of action have remained elusive, especially in the early phase of infection. We found that Spi-B-deficient mice had increased numbers of mast cells...
Annual Review of Immunology 35 119-147 2017年4月 [査読有り]
The intestinal epithelial barrier includes columnar epithelial, Paneth, goblet, enteroendocrine, and tuft cells as well as other cell populations, all of which contribute properties essential for gastrointestinal homeostasis. The intestinal mucosa...
Extracellular adenosine 5'-triphosphate (ATP) performs multiple functions including activation and induction of apoptosis of many cell types. The ATP-hydrolyzing ectoenzyme ecto-nucleotide pyrophosphatase/phosphodiesterase 3 (E-NPP3) regulates ATP...
Ogata H   Narentonglega   Tanaka I   Matsukura F   Morimoto M   Kiyono H   Nakano T   Hamada H   Kurashima Y   
Dr. Toshinori Nakayama Memorial cMAV-cSIMVa Workshop 2024年1月20日
Zhang Z   Shimada K   Saito Y   Ernst BP   Matsumoto Y   Ohira G   Matsubara H   Kiyono H   Kurashima Y   
Dr. Toshinori Nakayama Memorial cMAV-cSIMVa Workshop 2024年1月20日
Sasa H   Saito S   Wu Y   Zhang Z   Murasaki S   He J   Narentonglega   Kiyono H   Kurashima Y   
Dr. Toshinori Nakayama Memorial cMAV-cSIMVa Workshop 2024年1月20日