Brain research bulletin 204 110788-110788 Nov 2023
Xenin is a 25-amino acid peptide identified in human gastric mucosa, which is widely expressed in peripheral and central tissues. It is known that the central or peripheral administration of xenin decreases food intake in rodents. Nesfatin-1/NUCB2...
Journal of pharmacological sciences 150(4) 201-203 Dec 2022
Currently, the emergence of drug resistance is an important issue in the treatment of hepatitis B virus (HBV). Recently, our collaborating group developed a novel long-acting anti-HBV drug, E-CFCP. However, until this study, the effects of E-CFCP ...
Ischemic tolerance is a phenomenon in which resistance to subsequent invasive ischemia is acquired by a preceding noninvasive ischemic application, and is observed in many organs, including the brain, the organ most vulnerable to ischemic insult. ...
Tanaka M, Shigetomi E, Parajuli B, Nagatomo H, Shinozaki Y, Hirayama Y, Saito K, Kubota Y, Danjo Y, Lee JH, Kim SK, Nabekura J, Koizumi S.
Glia 69(11) 2546-2558 2021 [Refereed]
Metabotropic glutamate receptor 5 (mGluR5) in astrocytes is a key molecule for controlling synapse remodeling. Although mGluR5 is abundant in neonatal astrocytes, its level is gradually down-regulated during development and is almost absent in the...
Mechanisms underlying glia-mediated ischemic toleranceJapan Society for the Promotion of Science: Grants-in-Aid for Scientific ResearchKOIZUMI Schuichi HIRAYAMA Yuri KINOUCHI Hiroyuki SHINOZAKI Youichi SHIGETOMI Eiji
○○学科