Ihara T, Mitsui T, Nakamura Y, Kira S, Miyamoto T, Nakagomi H, Sawada N, Hirayama Y, Shibata K, Shigetomi E, Shinozaki Y, Yoshiyama M, Andersson KE, Nakao A, Takeda M, Koizumi S.   
NEUROUROLOGY AND URODYNAMICS 36(4) 1034-1038 2017年4月 [査読有り]
AimsThe pathophysiologies of nocturia (NOC) and nocturnal polyuria (NP) are multifactorial and their etiologies remain unclear in a large number of patients. Clock genes exist in most cells and organs, and the products of Clock regulate circadian ...
Ihara T, Mitsui T, Nakamura Y, Kira S, Nakagomi H, Sawada N, Hirayama Y, Shibata K, Shigetomi E, Shinozaki Y, Yoshiyama M, Andersson KE, Nakao A, Takeda M, Koizumi S.   
PLOS ONE 12(1) 2017年1月 [査読有り]
Objectives
Clock(Delta 19/Delta 19) mice is an experimental model mouse for nocturia (NOC). Using the bladder mucosa obtained from Clock(Delta 19/Delta 19) mice, we investigated the gene expression rhythms of mechanosensory cation channels such as...
Hirayama Y   Ikeda-Matsuo Y   Notomi S   Enaida H   Kinouchi H   Koizumi S   
JOURNAL OF NEUROSCIENCE 35(9) 3794-3805 2015年3月 [査読有り]
Preconditioning (PC) using a preceding sublethal ischemic insult is an attractive strategy for protecting neurons by inducing ischemic tolerance in the brain. Although the underlying molecular mechanisms have been extensively studied, almost all s...